Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.54 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL141739 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Ethylenediamine SCHEMBL2096846 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL22462332 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL8852034 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL5462536 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL27961273 | 0.95 | SOAT1 (0.61) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28284148 | 0.95 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL21218811 | 0.95 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Propylamine SCHEMBL27953558 | 0.95 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL28709026 | 0.93 | MEN1 (0.59) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137880-A1 | ELECTRONIC PACKAGES, HOUSINGS OR PACKAGES HAVING ONE OR MORE APERTURES | RJR TECHNOLOGIES, INC. (US) | 2017-08-17 | — | — | WO | disclosed |
| US-9580570-B2 | Rigid polyurethane resin for cutting work | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20140288198-A1 | RIGID POLYURETHANE RESIN FOR CUTTING WORK | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-25 | — | — | US | disclosed |
| EP-1006133-B2 | POLYURETHANE FOAM, PROCESS FOR PRODUCING THE SAME, AND FOAM FORMING COMPOSITION | SANYO CHEMICAL IND LTD (JP) | 2012-01-04 | — | — | EP | disclosed |
| EP-1006133-B9 | POLYURETHANE FOAM, PROCESS FOR PRODUCING THE SAME, AND FOAM FORMING COMPOSITION | SANYO CHEMICAL IND LTD (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1006133-B1 | POLYURETHANE FOAM, PROCESS FOR PRODUCING THE SAME, AND FOAM FORMING COMPOSITION | SANYO CHEMICAL IND LTD (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-1415335-B1 | USE OF DIVERSE MATERIALS IN AIR-CAVITY PACKAGING OF ELECTRONIC DEVICES | RJR POLYMERS INC (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1415335-A4 | USE OF DIVERSE MATERIALS IN AIR-CAVITY PACKAGING OF ELECTRONIC DEVICES | RJR POLYMERS INC (US) | 2005-12-21 | — | — | EP | disclosed |
| EP-1415335-A1 | USE OF DIVERSE MATERIALS IN AIR-CAVITY PACKAGING OF ELECTRONIC DEVICES | RJR Polymers, Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| US-6511866-B1 | Use of diverse materials in air-cavity packaging of electronic devices | RJR POLYMERS, INC. | 2003-01-28 | — | — | US | disclosed |
| EP-1171911-A1 | LEAD FRAME MOISTURE BARRIER FOR MOLDED PLASTIC ELECTRONIC PACKAGES | RJR Polymers, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6221929-B1 | POLYETHERURETHANE COPOLYMER | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-24 | — | — | US | disclosed |
| US-6214152-B1 | APPLYING HEAT CURABLE ADHESIVE; MOLDING; CURING | RJR POLYMERS, INC. | 2001-04-10 | — | — | US | disclosed |
| WO-2000057466-A1 | LEAD FRAME MOISTURE BARRIER FOR MOLDED PLASTIC ELECTRONIC PACKAGES | RJR POLYMERS, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| EP-1006133-A1 | POLYURETHANE FOAM, PROCESS FOR PRODUCING THE SAME, AND FOAM FORMING COMPOSITION | SANYO CHEMICAL INDUSTRIES, Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |
| EP-0580764-B1 | CURABLE RESINS WITH SOLID SUPPORTED ANTIFOAMING AGENTS | MINNESOTA MINING & MFG (US) | 1997-01-02 | — | — | EP | disclosed |
| US-5401785-A | Foamed polyurethane-forming composition, foamed polyurethane and process making the same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0580764-A1 | CURABLE RESINS WITH SOLID SUPPORTED ANTIFOAMING AGENTS. | MINNESOTA MINING & MFG (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5206064-A | CURABLE RESINS WITH SOLID SUPPORTED ANTIFOAMING AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| WO-1992018550-A1 | CURABLE RESINS WITH SOLID SUPPORTED ANTIFOAMING AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-29 | — | — | WO | disclosed |