Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424277 | 0.93 | GAA (0.55) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL12424501 | 0.91 | GAA (0.58) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL8427983 | 0.86 | PKM (0.47) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL14174886 | 0.86 | GAA (0.56) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL8429458 | 0.85 | HSD17B10 (0.66) | GAALMNASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL8430234 | 0.85 | PKM (0.43) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL17815921 | 0.84 | GAA (0.57) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL20259413 | 0.83 | PKM (0.48) | GAALMNASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14424584 | 0.81 | GAA (0.64) | GAALMNASMN1; SMN2PKMRECQL | |
| SCHEMBL18909382 | 0.81 | TSHR (0.61) | GAALMNASMN1; SMN2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| EP-1857459-A2 | Pyrazolopyrimidine compound and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |