Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12385846 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1ALOX15POLBLMNA | |
| SCHEMBL16362467 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1ALOX15POLBLMNA | |
| SCHEMBL1928970 | 0.89 | — | — | |
| SCHEMBL25633196 | 0.89 | — | — | |
| SCHEMBL17900496 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1ALOX15POLBLMNA | |
| SCHEMBL986628 | 0.79 | OPRM1 (0.34) | ALDH1A1CYP2C9IRAK4KMT2AMEN1 | |
| SCHEMBL897562 | 0.79 | OPRM1 (0.34) | ALDH1A1CYP2C9IRAK4KMT2AMEN1 | |
| SCHEMBL988738 | 0.79 | DPP4 (0.37) | POLBLMNAKMT2AMEN1DPP4 | |
| SCHEMBL897563 | 0.79 | OPRM1 (0.34) | ALDH1A1CYP2C9IRAK4KMT2AMEN1 | |
| SCHEMBL989317 | 0.79 | DPP4 (0.37) | POLBLMNAKMT2AMEN1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |