Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582412 | 0.84 | SRD5A2 (0.59) | ACHECES2LMNASRD5A2VNN1 | |
| SCHEMBL32670780 | 0.84 | SRD5A2 (0.59) | ACHECES2LMNASRD5A2VNN1 | |
| SCHEMBL28562659 | 0.80 | CES2 (0.58) | CES2LMNASRD5A2MAOBKCNK3 | |
| SCHEMBL4517127 | 0.77 | MAPT (0.50) | ACHEALDH1A1KMT2A | |
| SCHEMBL4517129 | 0.77 | MAPT (0.50) | ACHEALDH1A1KMT2A | |
| SCHEMBL4517619 | 0.77 | MAPT (0.50) | ACHEALDH1A1KMT2A | |
| SCHEMBL16033121 | 0.77 | KMT2A (0.42) | ACHECES2LMNASRD5A2MAOB | |
| SCHEMBL31560802 | 0.75 | PTPN5 (0.45) | ACHELMNAKCNK3MEN1KMT2A | |
| SCHEMBL31560818 | 0.75 | KCNN4 (0.53) | ACHECES2 | |
| SCHEMBL16032904 | 0.74 | KMT2A (0.40) | ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075184-A2 | 2-ARYL-2-FLUOROPROPANOIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' PHA.R.MA S.P.A. (IT) | 2008-06-26 | — | — | WO | disclosed |