Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 12/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.49 |
| ▸ | TUBB | P07437 | 9/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175307 | 0.90 | TUBB1 (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Oxi-4503 SCHEMBL29370292 | 0.88 | CYP1A1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Oxi-4503 SCHEMBL12677563 | 0.88 | CYP1A1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14175308 | 0.88 | CYP1A1 (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14175295 | 0.88 | CYP1A1 (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Oxi-4503 SCHEMBL30934510 | 0.87 | CYP1A1 (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14175305 | 0.86 | TUBB1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145728 | 0.84 | CYP1A1 (0.38) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14175304 | 0.84 | TUBB1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14175316 | 0.82 | CYP1A1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384925-B2 | 2' Hydroxy-3'-bromo-3,4,4',5-tetramethoxy-(Z)-stilbene; antimitotic agent; inhibits the assembly of tubulin into microtubules; anticarcinogenic: solid tumor cancers, neovascularization; tubulin-binding stilbenoid analogs structurally related to combretastatin A-1 and A-4 (extract from willow tree) | OXIGENE, INC. (US) | 2008-06-10 | — | — | US | disclosed |