Oxi-4503

Oxi-4503

SCHEMBL29370292

COc1cc(/C=C\c2ccc(OC)c(OP(=O)(O)O)c2OP(=O)(O)O)cc(OC)c1OC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 3/20 0.54
CYP1B1 Q16678 3/20 0.54
CYP1A2 P05177 2/20 0.52
TUBB1 Q9H4B7 11/20 0.50
TUBB4A P04350 8/20 0.50
TUBB P07437 8/20 0.50
TUBA3C P0DPH7 8/20 0.50
TUBA1B P68363 8/20 0.50
TUBA4A P68366 8/20 0.50
TUBB4B P68371 8/20 0.50
TUBB3 Q13509 8/20 0.50
TUBB2A Q13885 8/20 0.50
TUBB8 Q3ZCM7 8/20 0.50
TUBA3E Q6PEY2 8/20 0.50
TUBA1A Q71U36 8/20 0.50
TUBA1C Q9BQE3 8/20 0.50
TUBB6 Q9BUF5 8/20 0.50
TUBB2B Q9BVA1 8/20 0.50
SLC22A2 O15244 1/20 0.50
SLCO2B1 O94956 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxi-4503 SCHEMBL12677563 1.00 CYP1A1 (0.54) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
Oxi-4503 SCHEMBL30934510 0.99 CYP1A1 (0.52) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175308 0.97 CYP1A1 (0.57) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175295 0.97 CYP1A1 (0.57) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175305 0.90 TUBB1 (0.51) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175304 0.90 TUBB1 (0.51) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175316 0.88 CYP1A1 (0.49) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175307 0.88 TUBB1 (0.50) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL14175299 0.88 TUBB1 (0.50) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A
SCHEMBL13724720 0.88 CYP1A1 (0.55) CYP1A1CYP1B1CYP1A2TUBB1TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313156-B1 DISULFIDE-BASED PRODRUG COMPOUNDS UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2025-08-06 EP claimed
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2024-06-27 US claimed
US-20240156965-A1 DICHALCOGENIDE PRODRUGS LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2024-05-16 US claimed
EP-4320124-A1 DICHALCOGENIDE PRODRUGS Ludwig-Maximilians-Universität München (DE) 2024-02-14 EP claimed
EP-4313156-A1 DISULFIDE-BASED PRODRUG COMPOUNDS Ludwig-Maximilians-Universität München (DE) 2024-02-07 EP claimed
US-20220401556-A1 USE OF VDAS TO ENHANCE IMMUNOMODULATING THERAPIES AGAINST TUMORS ONCOTELIC THERAPEUTICS, INC. 2022-12-22 US claimed
WO-2022214598-A1 DICHALCOGENIDE PRODRUGS LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2022-10-13 WO claimed
EP-4071148-A1 DICHALCOGENIDE PRODRUGS Ludwig-Maximilians-Universität München (DE) 2022-10-12 EP claimed
WO-2022200347-A1 DISULFIDE-BASED PRODRUG COMPOUNDS LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2022-09-29 WO claimed
EP-4062942-A1 DISULFIDE-BASED PRODRUG COMPOUNDS Ludwig-Maximilians-Universität München (DE) 2022-09-28 EP claimed
US-11419934-B2 Use of VDAS to enhance immunomodulating therapies against tumors ONCOTELIC THERAPEUTICS, INC. (US) 2022-08-23 US claimed
US-20260144799-A1 COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER Revolution Medicines, Inc. (US) 2026-05-28 US disclosed
US-12636250-B2 Microneedle array patches (MAPs), systems, and methods for manufacturing and using same TERRESTRIAL BIO, INC. (US) 2026-05-26 US disclosed
US-12637445-B2 KIF18A inhibitors AMGEN INC. (US) 2026-05-26 US disclosed
US-20260139051-A1 COMBINATION THERAPIES USING MOLECULES BINDING TO TCR MARENGO THERAPEUTICS INC (US) 2026-05-21 US disclosed
WO-2022047046-A1 METHODS OF DETECTING TRBC1 OR TRBC2 MARENGO THERAPEUTICS, INC. (US) 2022-03-03 WO disclosed
US-20220064297-A1 ANTI-TCR ANTIBODY MOLECULES AND USES THEREOF MARENGO THERAPEUTICS, INC. 2022-03-03 US disclosed
WO-2022046920-A2 MULTIFUNCTIONAL MOLECULES THAT BIND TO CALRETICULIN AND USES THEREOF MARENGO THERAPEUTICS, INC. (US) 2022-03-03 WO disclosed
US-20220056015-A1 KIF18A INHIBITORS AMGEN INC. (US) 2022-02-24 US disclosed
US-11236069-B2 KIF18A inhibitors AMGEN INC. (US) 2022-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636250-B2 Microneedle array patches (MAPs), systems, and methods for manufacturing and using same GLP1R, NPY1R, NPY4R CYP1A1 2639/4885CYP1B1 2617/4885CYP1A2 2523/4885
US-20220401556-A1 USE OF VDAS TO ENHANCE IMMUNOMODULATING THERAPIES AGAINST TUMORS CD274, PDCD1LG2, PDCD1 CYP1A1 3411/4885CYP1B1 3624/4885CYP1A2 3828/4885
US-12637445-B2 KIF18A inhibitors KIF18A, KIF18B, KIF2C CYP1A1 3727/4885CYP1B1 3233/4885CYP1A2 3875/4885
US-20260144799-A1 COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER PDCD1, CD274, PTPN1 CYP1A1 3822/4885CYP1B1 3903/4885CYP1A2 4557/4885
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND CBS, MSR1, P4HB CYP1A1 827/4885CYP1B1 656/4885CYP1A2 1247/4885
US-20240156965-A1 DICHALCOGENIDE PRODRUGS DHCR7, DECR1, CYP27A1 CYP1A1 593/4885CYP1B1 772/4885CYP1A2 714/4885
US-20260139051-A1 COMBINATION THERAPIES USING MOLECULES BINDING TO TCR CD2, CD4, CD47 CYP1A1 4242/4885CYP1B1 4536/4885CYP1A2 4551/4885
US-11236069-B2 KIF18A inhibitors KIF18A, KIF18B, KIF15 CYP1A1 2801/4885CYP1B1 2424/4885CYP1A2 2449/4885
US-20220056015-A1 KIF18A INHIBITORS KIF18A, KIF18B, KIF15 CYP1A1 3329/4885CYP1B1 2858/4885CYP1A2 2959/4885
US-11419934-B2 Use of VDAS to enhance immunomodulating therapies against tumors CD274, PDCD1LG2, CA4 CYP1A1 3326/4885CYP1B1 3655/4885CYP1A2 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.