Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 4/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175344 | 0.88 | CDK1 (0.42) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL6055370 | 0.87 | CDK1 (0.37) | CCNB2CDK1CCNB1CCNB3TYMP | |
| SCHEMBL14175352 | 0.84 | CCNB2 (0.42) | CCNB2CDK1CCNB1CCNB3SLC6A1 | |
| SCHEMBL14175383 | 0.84 | CDK1 (0.44) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175381 | 0.84 | CDK1 (0.42) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175353 | 0.83 | CCNB2 (0.39) | CCNB2CDK1CCNB1CCNB3SLC6A1 | |
| SCHEMBL14175343 | 0.83 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL6055218 | 0.80 | CDK1 (0.39) | CCNB2CDK1CCNB1CCNB3TYMP | |
| SCHEMBL14175370 | 0.80 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3SLC6A1 | |
| SCHEMBL14175354 | 0.80 | CDK1 (0.43) | CCNB2CDK1CCNB1CCNB3SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |