Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 6/20 | 0.39 |
| ▸ | CDK1 | P06493 | 6/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175352 | 0.87 | CCNB2 (0.42) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175379 | 0.87 | CDK1 (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175363 | 0.84 | CDK1 (0.44) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175344 | 0.84 | CDK1 (0.42) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175338 | 0.83 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175354 | 0.83 | CDK1 (0.43) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175370 | 0.83 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175358 | 0.82 | CDK1 (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175351 | 0.82 | CCNB2 (0.44) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175381 | 0.80 | CDK1 (0.42) | CCNB2CDK1CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |