Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176659 | 0.97 | ALDH1A1 (0.43) | ALDH1A1RBP4KDM4EL3MBTL1MEN1 | |
| SCHEMBL14177068 | 0.91 | MEN1 (0.48) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL2259427 | 0.90 | ALDH1A1 (0.44) | ALDH1A1RBP4KDM4EL3MBTL1MEN1 | |
| SCHEMBL2257229 | 0.88 | KDM4E (0.53) | ALDH1A1RBP4KDM4EL3MBTL1MEN1 | |
| SCHEMBL2256762 | 0.86 | KDM4E (0.57) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL2256551 | 0.85 | KDM4E (0.50) | ALDH1A1RBP4KDM4EL3MBTL1MEN1 | |
| SCHEMBL2258557 | 0.84 | MEN1 (0.48) | ALDH1A1RBP4KDM4EL3MBTL1MEN1 | |
| SCHEMBL2259046 | 0.84 | MAPT (0.47) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL2255578 | 0.84 | GAA (0.56) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL2257410 | 0.84 | MEN1 (0.48) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073825-A1 | LXR AND FXR MODULATORS | EXELIXIS, INC. (US) | 2008-06-19 | — | — | WO | disclosed |