Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865788 | 0.88 | TLR4 (0.50) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL1866600 | 0.87 | TLR4 (0.67) | TLR4KMT2ALMNATP53NPSR1 | |
| SCHEMBL27592447 | 0.87 | TLR4 (0.55) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL14176725 | 0.86 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4138878 | 0.85 | TLR4 (0.48) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4146514 | 0.85 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL14136690 | 0.85 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4141115 | 0.85 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL17727727 | 0.85 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4144992 | 0.85 | TLR4 (0.46) | TLR4KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935879-A1 | SUBSTITUTED CYCLOALKENE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-06-25 | — | — | EP | disclosed |