Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176734 | 0.87 | TLR4 (0.51) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL871509 | 0.86 | TLR4 (0.73) | TLR4KMT2ALMNAMRGPRX1NPSR1 | |
| SCHEMBL1865788 | 0.85 | TLR4 (0.50) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL4140844 | 0.85 | TLR4 (0.50) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL14176725 | 0.83 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL14176475 | 0.83 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL4138878 | 0.82 | TLR4 (0.48) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL4144992 | 0.82 | TLR4 (0.46) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL4146514 | 0.81 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ATP53 | |
| SCHEMBL17727727 | 0.81 | TLR4 (0.49) | TLR4KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-A | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | TAKEDA PHARMACEUTICAL | 2012-12-12 | — | — | CN | disclosed |
| CN-102670503-A | Stable emulsion composition | TAKEDA PHARMACEUTICAL | 2012-09-19 | — | — | CN | disclosed |
| CN-1416341-B | Stable emulsion compositions | TAKEDA CHEMICAL INDUSTRIES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-101212986-A | stable emulsified composition | TAKEDA PHARMACEUTICAL (JP) | 2008-07-02 | — | — | CN | disclosed |
| CN-1416341-A | Stable emulsion compsns | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | CN | disclosed |