Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15503300 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL12533554 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL30061260 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL30301362 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL29664909 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL15503174 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL22118102 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL14156065 | 0.92 | MAPT (0.53) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL408107 | 0.87 | LMNA (0.59) | MAPTLMNAHTTBLMKDM4E | |
| SCHEMBL15982303 | 0.86 | MAPT (0.59) | MAPTLMNAHTTBLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145800-A1 | PHOTOTHERMOGRAPHIC MATERIALS CONTAINING DEVELOPER AND CO-DEVELOPER | CARESTREAM HEALTH, INC. | 2008-06-19 | — | — | US | disclosed |
| US-7267935-B1 | Thermally developable materials stabilized with crown ethers | CARESTREAM HEALTH, INC. (US) | 2007-09-11 | — | — | US | disclosed |