Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.68 |
| ▸ | F10 | P00742 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536184 | 0.90 | F10 (0.84) | F2F10KDM4EPDE5ASCD | |
| SCHEMBL14177134 | 0.87 | F2 (0.62) | F2F10ALDH1A1MEN1KMT2A | |
| SCHEMBL14227922 | 0.81 | KDM4E (0.61) | KDM4EPDE5ASCDALDH1A1MEN1 | |
| SCHEMBL3538043 | 0.81 | F10 (1.00) | F2F10KDM4EPDE5ASCD | |
| SCHEMBL3537566 | 0.80 | F10 (0.94) | F2F10KDM4EPDE5ASCD | |
| SCHEMBL3537852 | 0.80 | F2 (0.86) | F2F10KDM4ESCDALDH1A1 | |
| SCHEMBL5183594 | 0.79 | F10 (0.76) | F2F10KDM4EPDE5ASCD | |
| SCHEMBL3538270 | 0.79 | F2 (0.78) | F2F10KDM4EALDH1A1MEN1 | |
| SCHEMBL3536649 | 0.79 | F2 (0.84) | F2F10KDM4ESCDALDH1A1 | |
| SCHEMBL3537641 | 0.79 | F10 (0.78) | F2F10KDM4EPDE5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146550-A1 | HETEROARYLACETAMIDE INHIBITORS OF FACTOR Xa | BOEHRINGER MARKUS | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146550-A1 | HETEROARYLACETAMIDE INHIBITORS OF FACTOR Xa | F12, TFPI, F2 | F2 3/4885F10 9/4885KDM4E 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.