Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | PDE5A | O76074 | 2/20 | 0.61 |
| ▸ | SCD | O00767 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PDE1A | P54750 | 1/20 | 0.51 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599948 | 0.87 | KDM4E (0.78) | KDM4EPDE5ASCDALDH1A1SMN1; SMN2 | |
| SCHEMBL3544268 | 0.86 | SCD (0.65) | KDM4EPDE5ASCDALDH1A1ADORA3 | |
| SCHEMBL8696917 | 0.86 | KDM4E (0.77) | KDM4EPDE5ASCDALDH1A1MEN1 | |
| SCHEMBL5717720 | 0.86 | MEN1 (0.70) | KDM4EPDE5ASCDALDH1A1MEN1 | |
| SCHEMBL14177135 | 0.81 | F2 (0.68) | KDM4EPDE5ASCDALDH1A1ADORA3 | |
| SCHEMBL4637561 | 0.77 | SCD (0.60) | KDM4EPDE5ASCDALDH1A1MAPT | |
| SCHEMBL5717593 | 0.77 | GAA (0.67) | KDM4EPDE5ASCDALDH1A1ADORA3 | |
| SCHEMBL5717620 | 0.77 | KDM4E (0.74) | KDM4EPDE5ASCDADORA3SMN1; SMN2 | |
| SCHEMBL3621458 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11359245 | 0.75 | GABRA5 (0.57) | KDM4EPDE5ASCDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361672-B2 | Heteroarylacetamide inhibitors of factor Xa | HOFFMANN-LA ROCHE INC. (US) | 2008-04-22 | — | — | US | disclosed |