SCHEMBL14178264

SCHEMBL14178264

CNCCCN(C)CCCCCCNC(=N)OC

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
S1PR5 Q9H228 1/20 0.35
CHRM2 P08172 3/20 0.34
EPHX1 P07099 2/20 0.33
KDM4A O75164 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
APP P05067 2/20 0.32
KDM5A P29375 1/20 0.31
PRMT3 O60678 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
PRMT1 Q99873 1/20 0.30
PRMT8 Q9NR22 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14178275 1.00 S1PR2 (0.35) S1PR2S1PR1S1PR3S1PR5CHRM2
SCHEMBL14178254 0.87 EPHX1 (0.42) EPHX1KDM4AKDM4C
SCHEMBL14178259 0.87 EPHX1 (0.42) EPHX1KDM4AKDM4C
SCHEMBL14178258 0.87 EPHX1 (0.42) EPHX1KDM4AKDM4C
SCHEMBL14178222 0.81 EPHX1 (0.48) S1PR2S1PR1S1PR3S1PR5CHRM2
SCHEMBL19546063 0.79 PRMT3 (0.46) S1PR2S1PR1S1PR3S1PR5CHRM2
SCHEMBL22946807 0.79 EPHX1 (0.50) S1PR2S1PR1S1PR3S1PR5CHRM2
SCHEMBL1229873 0.79 EPHX1 (0.50) S1PR2S1PR1S1PR3S1PR5CHRM2
SCHEMBL14178280 0.78 KDM1A (0.38) S1PR2S1PR1S1PR3S1PR5EPHX1
SCHEMBL14178269 0.78 KDM1A (0.38) S1PR2S1PR1S1PR3S1PR5EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371852-B2 Alkyl-linked nucleotide compositions SERENEX, INC. (US) 2008-05-13 US disclosed