SCHEMBL1417829

SCHEMBL1417829

CC(=Cc1ccc2c([nH]c3ccccc32)c1C=Cc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.44
GLA P06280 7/20 0.44
NPC1 O15118 6/20 0.44
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
RAB9A P51151 5/20 0.44
KDM4E B2RXH2 5/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
ATM Q13315 2/20 0.44
MAPK1 P28482 1/20 0.44
AKR1C3 P42330 1/20 0.43
LMNA P02545 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
HTT P42858 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ALDH1A1 P00352 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2411424 0.83 AKR1C3 (0.39) MAPTGLANPC1MEN1KMT2A
Benzene SCHEMBL29250968 0.82 MAPT (0.58) MAPTGLANPC1MEN1KMT2A
SCHEMBL52089 0.82 MAPT (0.58) MAPTGLANPC1MEN1KMT2A
SCHEMBL63315 0.82 MAPT (0.58) MAPTGLANPC1MEN1KMT2A
SCHEMBL9503175 0.81 PIM3 (0.39) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL252615 0.79 PARP14 (0.47) MAPTKDM4EMAPK1AKR1C3LMNA
SCHEMBL9452537 0.78 MAPT (0.51) MAPTGLANPC1MEN1KMT2A
SCHEMBL9502084 0.70 PIM3 (0.44) MAPTGLANPC1MEN1KMT2A
SCHEMBL8746661 0.69 AKR1C3 (0.61) MAPTMEN1KMT2AKDM4EAKR1C3
SCHEMBL7117038 0.69 GLA (0.59) MAPTGLANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105027004-B Lighographic printing plate precursor and purposes 伊斯曼柯达公司 2019-06-11 CN disclosed
EP-2033051-B1 NEGATIVE-WORKING IMAGEABLE ELEMENTS EASTMAN KODAK CO (US) 2016-11-30 EP disclosed
EP-2470369-B1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND STACKS EASTMAN KODAK CO (US) 2014-03-19 EP disclosed
EP-2297611-B1 ON-PRESS DEVELOPABLE IMAGEABLE ELEMENTS EASTMAN KODAK CO (US) 2012-07-11 EP disclosed
EP-2470369-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND STACKS Eastman Kodak Company (US) 2012-07-04 EP disclosed
EP-2297611-A1 ON-PRESS DEVELOPABLE IMAGEABLE ELEMENTS Eastman Kodak Company (US) 2011-03-23 EP disclosed
WO-2011028393-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND STACKS EASTMAN KODAK COMPANY (US) 2011-03-10 WO disclosed
WO-2010005488-A1 ON-PRESS DEVELOPABLE IMAGEABLE ELEMENTS EASTMAN KODAK COMPANY (US) 2010-01-14 WO disclosed
EP-2033051-A2 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE ELEMENT EASTMAN KODAK COMPANY (US) 2009-03-11 EP disclosed
US-7452638-B2 Negative-working radiation-sensitive compositions and imageable materials EASTMAN KODAK COMPANY (US) 2008-11-18 US disclosed
WO-2008036170-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS EASTMAN KODAK COMPANY (US) 2008-03-27 WO disclosed
US-20080070152-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS BANK OF AMERICA, N.A., AS AGENT 2008-03-20 US disclosed
US-20080008957-A1 Negative-working radiation-sensitive compositions and imageable elements EASTMAN KODAK COMPANY 2008-01-10 US disclosed
WO-2008002393-A2 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE ELEMENT EASTMAN KODAK COMPANY (US) 2008-01-03 WO disclosed