SCHEMBL14178463

SCHEMBL14178463

CC(=O)SSCC1OC(OP(=O)(O)OP(=O)(O)OCC2OC(n3cnc4c(=O)[nH]c(N)nc43)C(O)C2O)C(O)C(O)C1O

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FUT5 Q11128 1/20 0.67
TGM2 P21980 1/20 0.63
KRAS P01116 9/20 0.62
NT5E P21589 1/20 0.59
P2RY2 P41231 1/20 0.55
P2RY4 P51582 1/20 0.55
P2RY6 Q15077 1/20 0.55
P2RX3 P56373 1/20 0.55
DCPS Q96C86 1/20 0.55
HINT1 P49773 1/20 0.54
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
P2RY1 P47900 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14178436 0.92 FUT5 (0.69) FUT5TGM2KRASNT5EP2RY2
SCHEMBL27413479 0.89 FUT5 (0.74) FUT5TGM2KRASNT5EP2RY2
SCHEMBL25964282 0.89 FUT5 (0.74) FUT5TGM2KRASNT5EP2RY2
SCHEMBL14178440 0.88 FUT5 (0.71) FUT5TGM2KRASNT5EP2RY2
SCHEMBL29581866 0.88 FUT5 (0.73) FUT5TGM2KRASNT5EP2RY2
SCHEMBL30646153 0.88 FUT5 (0.73) FUT5TGM2KRASNT5EP2RY2
SCHEMBL29393705 0.88 FUT5 (0.73) FUT5TGM2KRASNT5EP2RY2
SCHEMBL29351374 0.88 FUT5 (0.73) FUT5TGM2KRASNT5EP2RY2
SCHEMBL29391942 0.88 FUT5 (0.73) FUT5TGM2KRASNT5EP2RY2
SCHEMBL30973673 0.88 FUT5 (0.73) FUT5TGM2KRASNT5EP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080108557-A1 Modified Proteins NOVO NORDISK HEALTHCARE A/G (CH) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080108557-A1 Modified Proteins PTMS, DNPEP, STT3A FUT5 198/4885TGM2 111/4885KRAS 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.