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Sugi Predict / Targets / FUT5

FUT5

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 · Q11128 · FUT5 on Sugi Atlas →

7,177 patent compounds predicted against FUT5, 5,349 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL851357 SCHEMBL851357 0.78 1/20
SCHEMBL2229602 SCHEMBL2229602 0.76 1/20
SCHEMBL2166452 SCHEMBL2166452 0.75 1/20
SCHEMBL6430315 SCHEMBL6430315 0.75 1/20
Guanosine Triphosphate Guanosine Triphosphate (SCHEMBL44408) 0.75 1/20
Gtp Gtp (SCHEMBL96708) 0.75 1/20
Gtp Gtp (SCHEMBL103832) 0.75 1/20
SCHEMBL376139 SCHEMBL376139 0.75 1/20
SCHEMBL376140 SCHEMBL376140 0.75 1/20
SCHEMBL1304258 SCHEMBL1304258 0.75 1/20
SCHEMBL1304259 SCHEMBL1304259 0.75 1/20
SCHEMBL2593095 SCHEMBL2593095 0.75 1/20
Gtp Gtp (SCHEMBL3333959) 0.75 1/20
Gtp Gtp (SCHEMBL5809658) 0.75 1/20
SCHEMBL932313 SCHEMBL932313 0.74 1/20
Guanosine Triphosphate Guanosine Triphosphate (SCHEMBL2284832) 0.74 1/20
SCHEMBL2513028 SCHEMBL2513028 0.74 1/20
SCHEMBL2706655 SCHEMBL2706655 0.74 1/20
SCHEMBL6692026 SCHEMBL6692026 0.74 1/20
SCHEMBL37405 SCHEMBL37405 0.73 1/20

Clinical trials — most relevant to FUT5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
BEFORE Study, Efficacy of Refigura PHASE4COMPLETED
Monosialoganglioside in Acute Ischemic Stroke: a Randomized, Blinded and Multicenter Confirmatory Study PHASE3COMPLETED
Multi-Center Study of ManNAc for GNE Myopathy PHASE2ACTIVE_NOT_RECRUITING
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental Glomerulosclerosis PHASE2RECRUITING
Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (H-R MDS) PHASE2COMPLETED
A Study of Monosialic Gangliosides to Prevent Albumin-bound Paclitaxel Neurotoxicity PHASE2COMPLETED
Vaccine Treatment for Hormone Refractory Prostate Cancer PHASE1/PHASE2COMPLETED
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases PHASE1COMPLETED
Autologous Stem Cell Transplantation of Cells Engineered to Express Alpha-Galactosidase A in Patients With Fabry Disease PHASE1COMPLETED
Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy PHASE1COMPLETED
68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients EARLY_PHASE1UNKNOWN
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption nanUNKNOWN
Sialic Acid Supplementation in N-Acetylneuraminic Acid Synthase (NANS) Deficiency nanCOMPLETED
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
Glycosylation in Patients With Galactosaemia nanCOMPLETED
The Natural History of Alpha-Mannosidosis nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
A Clinical Study to Assess the Effect of Increasing Intake Amounts of Two Novel Glycans on the Gut Microbiota of Healthy Subjects nanCOMPLETED
Glycan Attachment Specificity, Toward ROtavirus Vaccine IMprovement GASTROVIMc (Clinical Investigation) nanCOMPLETED
Evaluation of Blood and Cardiac Protein O-GlcNAcylation Levels in Cardiac Surgery in Children nanRECRUITING
Evaluation of Blood Protein O-GlcNAcylation Levels in Children nanRECRUITING
Registry Gangliosidoses nanUNKNOWN
Biomarker for Gangliosidosis: BioGM1/BioGM2 (BioGM1/GM2) nanWITHDRAWN
The Effect of Galactooligosaccharides (GOS) on the Gut Microbiota of Lactose Intolerance Individuals nanCOMPLETED
GI Alpha-Gal Study nanCOMPLETED
Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing nanUNKNOWN
Galectin 3 Dosage in Diagnosis of Nodular and Multinodular Goiter nanCOMPLETED
Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a FUT5 binder may also engage these)

ProteinNameSimilarity
P56433 — 1.000 P56433 →
Q8HYJ5 — 1.000 Q8HYJ5 →
Q8HYJ3 — 1.000 Q8HYJ3 →
Q8HYJ4 — 1.000 Q8HYJ4 →
Q8HYJ7 — 1.000 Q8HYJ7 →
O19058 — 1.000 O19058 →
Q11126 — 1.000 Q11126 →
P56434 — 0.999 P56434 →
Q9GKU6 — 0.998 Q9GKU6 →
Q8HYJ6 — 0.998 Q8HYJ6 →
FUT6 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 0.996 landscape →
P21217 — 0.996 P21217 →
Q8HZR3 — 0.991 Q8HZR3 →
Q712G6 — 0.991 Q712G6 →
Q11131 — 0.989 Q11131 →
Q62994 — 0.984 Q62994 →
FUT7 Alpha-(1,3)-fucosyltransferase 7 0.983 landscape →
Q11127 — 0.976 Q11127 →
G3MZR2 — 0.976 G3MZR2 →
Q29043 — 0.971 Q29043 →
Q9TUD6 — 0.971 Q9TUD6 →
O09008 — 0.968 O09008 →
Q866F1 — 0.968 Q866F1 →
Q866C9 — 0.968 Q866C9 →
Q866E1 — 0.967 Q866E1 →
Q866E8 — 0.967 Q866E8 →
Q866D9 — 0.967 Q866D9 →
P19526 — 0.967 P19526 →
Q866C7 — 0.967 Q866C7 →
Q866D6 — 0.966 Q866D6 →