Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180976 | 0.88 | CNR1 (0.52) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL4800125 | 0.87 | CNR1 (0.70) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL14180978 | 0.87 | CNR1 (0.64) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL14180759 | 0.86 | CNR1 (0.53) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL4798297 | 0.85 | CNR1 (0.50) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL4798404 | 0.85 | CNR1 (0.54) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL4797577 | 0.84 | CNR1 (0.54) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL14180857 | 0.84 | CNR1 (0.64) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL14180758 | 0.84 | CNR1 (0.53) | CNR1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL14180888 | 0.84 | CNR1 (0.58) | CNR1CYP3A4CYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |