Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180765 | 0.88 | CNR1 (0.56) | CNR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14180980 | 0.86 | CNR1 (0.60) | CNR1AGTR1AGTR2CYP3A4 | |
| SCHEMBL4798404 | 0.86 | CNR1 (0.54) | CNR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14180888 | 0.85 | CNR1 (0.58) | CNR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4804815 | 0.84 | CNR1 (0.52) | CNR1AGTR1AGTR2RAB9ANPC1 | |
| SCHEMBL4804639 | 0.84 | CNR1 (0.47) | CNR1AGTR1AGTR2RAB9ANPC1 | |
| SCHEMBL4804647 | 0.84 | CNR1 (0.47) | CNR1AGTR1AGTR2RAB9ANPC1 | |
| SCHEMBL4798297 | 0.84 | CNR1 (0.50) | CNR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4800125 | 0.83 | CNR1 (0.70) | CNR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14180978 | 0.83 | CNR1 (0.64) | CNR1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |