Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180963 | 0.90 | CNR1 (0.48) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14180961 | 0.90 | CNR1 (0.48) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14180756 | 0.89 | CNR1 (0.46) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4805929 | 0.88 | CNR1 (0.47) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14180951 | 0.87 | CNR1 (0.48) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14180952 | 0.86 | CNR1 (0.47) | CNR1MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL14180949 | 0.85 | CNR1 (0.47) | CNR1GPR119RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14180759 | 0.84 | CNR1 (0.53) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14180950 | 0.83 | KMT2A (0.46) | CNR1GPR119RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4804647 | 0.83 | CNR1 (0.47) | CNR1GPR119RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |