Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180952 | 0.92 | CNR1 (0.47) | CNR1LMNACA12ALDH1A1CA2 | |
| SCHEMBL14180955 | 0.91 | CNR1 (0.48) | CNR1LMNACA12ALDH1A1CA2 | |
| SCHEMBL14180958 | 0.91 | CNR1 (0.46) | CNR1LMNACA12ALDH1A1CA2 | |
| SCHEMBL14180950 | 0.87 | KMT2A (0.46) | CNR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14180963 | 0.86 | CNR1 (0.48) | CNR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14180961 | 0.86 | CNR1 (0.48) | CNR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4803516 | 0.85 | CNR1 (0.49) | CNR1ALDH1A1GPR119KMT2ASMN1; SMN2 | |
| SCHEMBL14180939 | 0.85 | CNR1 (0.47) | CNR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4805929 | 0.85 | CNR1 (0.47) | CNR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14180941 | 0.84 | CNR1 (0.49) | CNR1ALDH1A1GPR119KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |