Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180943 | 0.95 | CNR1 (0.52) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14180941 | 0.90 | CNR1 (0.49) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4804792 | 0.86 | CNR1 (0.50) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4804804 | 0.86 | CNR1 (0.50) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14180955 | 0.85 | CNR1 (0.48) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14180760 | 0.84 | CNR1 (0.67) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14180944 | 0.83 | CNR1 (0.56) | CNR1 | |
| SCHEMBL14180759 | 0.82 | CNR1 (0.53) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4798348 | 0.81 | CNR1 (0.56) | CNR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14181011 | 0.80 | CNR1 (0.75) | CNR1RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |