Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180952 | 0.92 | CNR1 (0.47) | CNR1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL14180958 | 0.91 | CNR1 (0.46) | CNR1CACNA1GKCNH2KMT2AMEN1 | |
| SCHEMBL14180949 | 0.91 | CNR1 (0.47) | CNR1RAB9AKMT2ANPC1TSHR | |
| SCHEMBL14180959 | 0.85 | CNR1 (0.50) | CNR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL14180961 | 0.85 | CNR1 (0.48) | CNR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL14180963 | 0.85 | CNR1 (0.48) | CNR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL14180950 | 0.84 | KMT2A (0.46) | CNR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL14180865 | 0.84 | CNR1 (0.51) | CNR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL4805929 | 0.83 | CNR1 (0.47) | CNR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL14180939 | 0.83 | CNR1 (0.47) | CNR1RAB9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |