Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800125 | 0.90 | CNR1 (0.70) | CNR1CYP3A4 | |
| SCHEMBL14180978 | 0.89 | CNR1 (0.64) | CNR1CYP3A4 | |
| SCHEMBL14180857 | 0.87 | CNR1 (0.64) | CNR1CYP3A4 | |
| SCHEMBL14180976 | 0.86 | CNR1 (0.52) | CNR1AGTR1AGTR2CYP3A4 | |
| SCHEMBL14180979 | 0.85 | CNR1 (0.62) | CNR1CYP3A4 | |
| SCHEMBL14180815 | 0.85 | CNR1 (0.64) | CNR1CYP3A4 | |
| SCHEMBL14180859 | 0.85 | CNR1 (0.64) | CNR1CYP3A4 | |
| SCHEMBL14180760 | 0.85 | CNR1 (0.67) | CNR1CYP3A4 | |
| SCHEMBL14180899 | 0.85 | CNR1 (0.64) | CNR1CYP3A4 | |
| SCHEMBL14180839 | 0.85 | CNR1 (0.64) | CNR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |