Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 16/20 | 0.69 |
| ▸ | SLC5A1 | P13866 | 10/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14181347 | 0.92 | SLC5A2 (0.69) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| SCHEMBL2577173 | 0.88 | SLC5A2 (0.79) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| SCHEMBL2573609 | 0.85 | SLC5A2 (0.74) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| SCHEMBL2574091 | 0.85 | SLC5A2 (0.78) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| SCHEMBL4007348 | 0.82 | SLC5A2 (0.69) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| SCHEMBL4007339 | 0.82 | SLC5A2 (0.69) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| Sergliflozin A SCHEMBL23436839 | 0.82 | SLC5A2 (1.00) | SLC5A2SLC5A1ACHE | |
| SCHEMBL2574895 | 0.82 | SLC5A2 (0.79) | SLC5A2SLC5A1ACHENPC1RAB9A | |
| Sergliflozin A SCHEMBL4361463 | 0.82 | SLC5A2 (1.00) | SLC5A2SLC5A1ACHE | |
| Sergliflozin A SCHEMBL2574820 | 0.82 | SLC5A2 (1.00) | SLC5A2SLC5A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371732-B2 | Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-7371732-B2 | Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-13 | — | — | US | disclosed |