Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16772328 | 0.93 | HTR2C (0.34) | SCN9AHTR2CALDH1A1MAPTCYP2C9 | |
| SCHEMBL14494615 | 0.91 | HTR2C (0.33) | HTR2CALDH1A1MAPTCYP2C9HTT | |
| SCHEMBL16772308 | 0.91 | KDM1A (0.32) | ALDH1A1MAPTCYP2C9HTTHTR2A | |
| SCHEMBL16772343 | 0.88 | HTR2C (0.32) | HTR2CALDH1A1MAPTHTTHTR2B | |
| SCHEMBL13328515 | 0.88 | ALDH1A1 (0.31) | ALDH1A1MAPTCYP2C9HTT | |
| SCHEMBL14181999 | 0.88 | GAA (0.34) | MAPTCYP2C9GAAMEN1MAPK1 | |
| SCHEMBL13328593 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPTCYP2C9HTTHTR2A | |
| SCHEMBL4402652 | 0.84 | SCN9A (0.38) | SCN9APPARGPTGESALOX5CNR2 | |
| SCHEMBL26209537 | 0.84 | SCN9A (0.38) | SCN9APPARGPTGESALOX5CNR2 | |
| SCHEMBL13328512 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MAPTCYP2C9HTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371437-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-20070051920-A1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-08 | — | — | US | disclosed |
| US-20070051920-A1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-08 | — | — | US | disclosed |