Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ITK | Q08881 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182639 | 1.00 | GRM4 (0.59) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182630 | 1.00 | GRM4 (0.59) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182636 | 1.00 | GRM4 (0.59) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182998 | 0.93 | GRM4 (0.59) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14183006 | 0.93 | GRM4 (0.59) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14183007 | 0.93 | GRM4 (0.59) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182641 | 0.91 | NPC1 (0.50) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182706 | 0.91 | NPC1 (0.50) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182634 | 0.88 | GRM4 (0.53) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14182698 | 0.87 | GRM4 (0.44) | GRM4NPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |