Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | ITK | Q08881 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK3 | P49761 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182690 | 1.00 | MAOA (0.65) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182711 | 1.00 | MAOA (0.65) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182624 | 1.00 | MAOA (0.65) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182718 | 0.96 | MAOA (0.57) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182692 | 0.93 | MAOA (0.70) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182629 | 0.93 | MAOA (0.70) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182633 | 0.93 | MAOA (0.70) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182679 | 0.93 | MAOA (0.70) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182717 | 0.91 | MAOA (0.53) | MAOAMAOBPTPN1ITKPOLB | |
| SCHEMBL14182723 | 0.91 | MAOA (0.53) | MAOAMAOBPTPN1ITKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |