Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182637 | 1.00 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14182731 | 0.92 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14182751 | 0.91 | KCNK3 (0.59) | RAB9ANPC1KCNK3KCNK9NAMPT | |
| SCHEMBL14182733 | 0.91 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14182750 | 0.91 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14182634 | 0.90 | GRM4 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1KCNK3 | |
| SCHEMBL14182640 | 0.89 | NAMPT (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14182777 | 0.85 | CES1 (0.54) | RAB9ANPC1MEN1KMT2AKCNK3 | |
| SCHEMBL14182876 | 0.85 | KCNK3 (0.53) | KCNK3KCNK9NAMPTPRMT5GRM4 | |
| SCHEMBL14182761 | 0.83 | KMT2A (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |