Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14185326 | 0.93 | KLK7 (0.47) | PTPN1KMT2ASIRT2SIRT1SIRT3 | |
| SCHEMBL17444823 | 0.92 | KLK7 (0.53) | KMT2ASIRT2SIRT1SIRT3KLK7 | |
| SCHEMBL14185323 | 0.90 | PTPN1 (0.45) | PTPN1KMT2ASIRT2SIRT1SIRT3 | |
| SCHEMBL30649009 | 0.90 | KMT2A (0.49) | PTPN1KMT2ATLR2TLR1 | |
| SCHEMBL26641096 | 0.90 | KMT2A (0.49) | PTPN1KMT2ATLR2TLR1 | |
| SCHEMBL30565186 | 0.89 | PTPN1 (0.55) | PTPN1HDAC1HDAC2 | |
| SCHEMBL14214788 | 0.88 | FOLH1 (0.52) | PTPN1KMT2ASIRT2SIRT1HDAC1 | |
| SCHEMBL24235733 | 0.88 | PTPN1 (0.51) | PTPN1KMT2AKLK7KLK5MAPT | |
| SCHEMBL29521232 | 0.88 | KLK7 (0.54) | KMT2AKLK7KLK5HDAC1HDAC2 | |
| SCHEMBL24235739 | 0.87 | PTPN1 (0.51) | PTPN1KMT2AKLK7KLK5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371724-B2 | KAPREKY peptidomimetics and analogues thereof | NOVARTIS AG (CH) | 2008-05-13 | — | — | US | disclosed |