Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214786 | 0.93 | FOLH1 (0.49) | FOLH1PTPN1KMT2ATLR2SIRT2 | |
| SCHEMBL23574786 | 0.90 | FOLH1 (0.58) | FOLH1KMT2ATLR2SIRT2SIRT1 | |
| SCHEMBL29400684 | 0.90 | FOLH1 (0.58) | FOLH1KMT2ATLR2SIRT2SIRT1 | |
| SCHEMBL23574788 | 0.90 | FOLH1 (0.58) | FOLH1KMT2ATLR2SIRT2SIRT1 | |
| SCHEMBL119447 | 0.90 | FOLH1 (0.58) | FOLH1KMT2ATLR2SIRT2SIRT1 | |
| SCHEMBL120774 | 0.90 | FOLH1 (0.58) | FOLH1KMT2ATLR2SIRT2SIRT1 | |
| SCHEMBL14185324 | 0.88 | PTPN1 (0.49) | FOLH1PTPN1KMT2ATLR2SIRT2 | |
| SCHEMBL8823890 | 0.87 | FOLH1 (0.62) | FOLH1KMT2ASIRT2SIRT1CPB1 | |
| SCHEMBL22804067 | 0.87 | FOLH1 (0.62) | FOLH1KMT2ASIRT2SIRT1CPB1 | |
| SCHEMBL178815 | 0.87 | FOLH1 (0.62) | FOLH1KMT2ASIRT2SIRT1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371724-B2 | KAPREKY peptidomimetics and analogues thereof | NOVARTIS AG (CH) | 2008-05-13 | — | — | US | disclosed |