SCHEMBL1418563

SCHEMBL1418563

O=C1CNCCS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9624300 1.00
SCHEMBL15766332 1.00
SCHEMBL22172529 0.76
Thiazolidinone SCHEMBL31220859 0.69
Thiazolidinone SCHEMBL11254207 0.69
SCHEMBL4558001 0.67
SCHEMBL3376530 0.67
SCHEMBL477205 0.67
SCHEMBL7954958 0.67
Water SCHEMBL27303508 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119799077-A Pigment dispersion liquid, photoresist composition, photosensitive glass and liquid crystal display device 阜阳欣奕华新材料科技股份有限公司 2025-04-11 CN claimed
CN-111087361-A Synthetic method of oxazoline-2-thioketone 厦门本素药业有限公司 2020-05-01 CN claimed
EP-1303301-B1 PREVENTING AIRWAY MUCUS PRODUCTION BY ADMINISTRATION OF EGF-R ANTAGONISTS UNIV CALIFORNIA (US) 2014-02-12 EP claimed
EP-2298746-A1 4-amino- quinazoline and quinoline derivatives having an inhibitory effect on signal transduction mediated by tyrosine kinases Boehringer Ingelheim Pharma GmbH & Co. KG (DE) 2011-03-23 EP claimed
CN-101316844-A Inhibitors of diacylglycerol acyltransferase (DGAT) HOFFMANN LA ROCHE (CH) 2008-12-03 CN claimed
EP-1157011-A1 4-AMINO- QUINAZOLINE AND QUINOLINE DERIVATIVES HAVING AN INHIBITORY EFFECT ON SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES Boehringer Ingelheim Pharma KG (DE) 2001-11-28 EP claimed
CN-1094030-A Diaminobenzoic acid derivatives CIBA GEIGY AG (CH) 1994-10-26 CN claimed
US-5135927-A 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid CIBA-GEIGY CORPORATION (US) 1992-08-04 US claimed
US-4992434-A Prevention of infestation of plants by phytopathogenic microorganisms CIBA-GEIGY CORPORATION (US) 1991-02-12 US claimed
US-12503439-B2 Heteroaryl compounds for the treatment of pain VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-23 US disclosed
US-11912721-B2 Fused pentacyclic imidazole derivatives UCB Biopharma SRL (BE) 2024-02-27 US disclosed
US-20230373925-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED 2023-11-23 US disclosed
US-20220017462-A1 ORTHO-PHTHALALDEHYDE CONTAINING LINKERS AND USE FOR PREPARATION OF ANTIBODY-DRUG CONJUGATE VERSITECH LIMITED (CN) 2022-01-20 US disclosed
CN-113474334-A Indazolyl-isoxazole derivatives for the treatment of diseases such as cancer 默克专利股份公司 2021-10-01 CN disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed
US-5135927-A 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid CIBA-GEIGY CORPORATION (US) 1992-08-04 US disclosed
US-4992434-A Prevention of infestation of plants by phytopathogenic microorganisms CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0107423-B1 NOVEL CHROMANS AND CHROMENES BEECHAM GROUP PLC (GB) 1986-07-23 EP disclosed
US-4496565-A HYPOTENSIVE AGENTS BEECHAM GROUP P.L.C. (GB) 1985-01-29 US disclosed
EP-0107423-A1 Novel chromans and chromenes BEECHAM GROUP PLC (GB) 1984-05-02 EP disclosed