SCHEMBL14186885

SCHEMBL14186885

CCCCCNC(=O)C(NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MTTP P55157 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1600315 1.00 MTTP (0.70) MTTP
SCHEMBL14132458 0.91 MTTP (0.68) MTTP
SCHEMBL6890386 0.86 MTTP (0.65) MTTP
SCHEMBL6255880 0.85 MTTP (0.91) MTTP
SCHEMBL4986838 0.85 MTTP (0.70) MTTP
SCHEMBL4986832 0.85 MTTP (0.70) MTTP
SCHEMBL5007646 0.82 MTTP (0.64) MTTP
SCHEMBL6254025 0.82 MTTP (1.00) MTTP
SCHEMBL5668283 0.82 MTTP (0.66) MTTP
SCHEMBL5011810 0.81 MTTP (0.64) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7368573-B2 Triamide-substituted heterobicyclic compounds PFIZER INC. (US) 2008-05-06 — — US disclosed
US-7368573-B2 Triamide-substituted heterobicyclic compounds PFIZER INC. (US) 2008-05-06 — — US disclosed
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