Hydrochloric Acid

Hydrochloric Acid

SCHEMBL141879

CC[n+]1c(C=C(C)O)sc2ccccc21.[Cl-]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.67
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 9/20 0.57
RAB9A P51151 7/20 0.57
POLB P06746 4/20 0.57
LMNA P02545 3/20 0.57
HPGD P15428 1/20 0.57
KMT2A Q03164 6/20 0.56
HTT P42858 6/20 0.56
MEN1 O00255 5/20 0.56
THRB P10828 3/20 0.56
MMP14 P50281 1/20 0.56
SMN1; SMN2 Q16637 5/20 0.54
NPC1 O15118 5/20 0.54
GAA P10253 2/20 0.54
NR2F2 P24468 1/20 0.54
RAD52 P43351 1/20 0.54
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29757621 1.00 MAPT (0.67) MAPTKDM4EALDH1A1RAB9APOLB
Hydrochloric Acid SCHEMBL1713242 1.00 MAPT (0.67) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL13046317 0.98 MAPT (0.69) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL8080554 0.98 MAPT (0.69) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL8080557 0.98 MAPT (0.69) MAPTKDM4EALDH1A1RAB9APOLB
Hydrochloric Acid SCHEMBL10952290 0.87 MAPT (0.62) MAPTKDM4EALDH1A1RAB9APOLB
Hydrochloric Acid SCHEMBL10952294 0.87 MAPT (0.62) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL11460155 0.82 MAPT (0.81) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL11460154 0.82 MAPT (0.81) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL13646767 0.82 MAPT (0.97) MAPTKDM4EALDH1A1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
WO-2000030632-A1 ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS EISAI CO., LTD. (JP) 2000-06-02 WO claimed
EP-0615854-B1 Recording sheets containing cationic sulphur compounds XEROX CORP (US) 1997-06-04 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0615854-A1 Recording sheets containing cationic sulphur compounds XEROX CORPORATION (US) 1994-09-21 EP claimed
US-5314747-A Recording sheets containing cationic sulfur compounds XEROX CORPORATION (US) 1994-05-24 US claimed
EP-3478792-B1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER INC (US) 2023-12-13 EP disclosed
CN-109642153-B Chemiluminescent substrate 拜克门寇尔特公司 2022-08-19 CN disclosed
US-10703971-B2 Chemiluminescent substrates BECKMAN COULTER, INC. (US) 2020-07-07 US disclosed
US-20190161675-A1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER, INC. (US) 2019-05-30 US disclosed
EP-2057275-B1 ARRAY FOR RAPID DETECTION OF A MICROORGANISM KIMBERLY CLARK CO (US) 2017-02-01 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
EP-0615854-A1 Recording sheets containing cationic sulphur compounds XEROX CORPORATION (US) 1994-09-21 EP disclosed
US-5314747-A Recording sheets containing cationic sulfur compounds XEROX CORPORATION (US) 1994-05-24 US disclosed