Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.36 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215483 | 1.00 | TDP1 (0.39) | TDP1P2RY6P2RY2P2RY4SLC28A1 | |
| SCHEMBL13523532 | 0.90 | POLB (0.39) | TDP1P2RY6P2RY2P2RY4 | |
| SCHEMBL13671118 | 0.90 | POLB (0.39) | TDP1P2RY6P2RY2P2RY4 | |
| SCHEMBL13523800 | 0.90 | POLB (0.39) | TDP1P2RY6P2RY2P2RY4 | |
| SCHEMBL15345855 | 0.86 | P2RY6 (0.36) | P2RY6P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL13592886 | 0.84 | POLB (0.41) | P2RY6P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL15281799 | 0.84 | POLB (0.41) | P2RY6P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL15345857 | 0.84 | P2RY6 (0.34) | P2RY6P2RY2P2RY4 | |
| SCHEMBL14188220 | 0.83 | LMNA (0.36) | P2RY2SLC29A1LMNATHRB | |
| SCHEMBL15345861 | 0.81 | P2RY6 (0.36) | P2RY6P2RY2P2RY4SLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378402-B2 | 4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; hepatitis C virus. | ROCHE PALO ALTO LLC (US) | 2008-05-27 | — | — | US | disclosed |