Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | NOS2 | P35228 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325590 | 0.86 | NOS3 (0.44) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL9813612 | 0.74 | CYP1A2 (0.37) | MAPTMEN1LMNAKMT2ATSHR | |
| SCHEMBL1941679 | 0.73 | NOS3 (0.49) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL1941677 | 0.73 | NOS3 (0.49) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL5326842 | 0.72 | GRIK1 (0.37) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL13958441 | 0.72 | KMT2A (0.45) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL23615876 | 0.71 | TAAR1 (0.38) | MAPTPMP22MPOCYP3A4NFKB1 | |
| SCHEMBL13971424 | 0.71 | SLC7A5 (0.69) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL9164980 | 0.71 | SLC7A5 (0.69) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL2267134 | 0.70 | NOS3 (0.43) | NOS3NOS1NOS2PKMSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146496-A1 | Novel Melanocortin Receptor Templates, Peptides, and Use Thereof | HASKELL-LUEVANO CARRIE | 2008-06-19 | — | — | US | disclosed |
| US-20080146779-A1 | Novel Melanocortin Receptor Templates, Peptides, and Use Thereof | HASKELL-LUEVANO CARRIE | 2008-06-19 | — | — | US | disclosed |