Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | SHBG | P04278 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1418970 | 1.00 | CYP19A1 (0.39) | CYP19A1SHBGCA1CA2CA9 | |
| SCHEMBL6880897 | 0.80 | SHBG (0.52) | CYP19A1SHBGRORARORCGPR183 | |
| SCHEMBL6876277 | 0.80 | SHBG (0.52) | CYP19A1SHBGRORARORCGPR183 | |
| SCHEMBL512330 | 0.80 | SHBG (0.52) | CYP19A1SHBGRORARORCGPR183 | |
| SCHEMBL6884200 | 0.80 | SHBG (0.52) | CYP19A1SHBGRORARORCGPR183 | |
| SCHEMBL512331 | 0.80 | SHBG (0.52) | CYP19A1SHBGRORARORCGPR183 | |
| SCHEMBL6453158 | 0.78 | CA1 (0.54) | CYP19A1SHBGCA1CA2CA9 | |
| SCHEMBL5190448 | 0.78 | CA1 (0.54) | CYP19A1SHBGCA1CA2CA9 | |
| SCHEMBL511028 | 0.78 | SHBG (0.40) | CYP19A1SHBGCA1CA2CA9 | |
| SCHEMBL511883 | 0.78 | CA1 (0.33) | SHBGCA1CA2CA9RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298316-A1 | Therapeutic treatment methods | Harbor BioSciences, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |