Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADM2 | Q7Z4H4 | 8/20 | 0.45 |
| ▸ | CALCB | P10092 | 7/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 12/20 | 0.43 |
| ▸ | RAMP1 | O60894 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898117 | 0.73 | CALCRL (0.45) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL13997603 | 0.72 | CALCRL (0.48) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL16602178 | 0.69 | CALCRL (0.51) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL13997597 | 0.68 | CALCRL (0.45) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL16602197 | 0.68 | CALCRL (0.42) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL16602176 | 0.67 | CALCRL (0.49) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL16602177 | 0.66 | CALCRL (0.47) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL22796627 | 0.66 | CALCRL (0.48) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL22796647 | 0.66 | CALCRL (0.48) | ADM2CALCBCALCRLRAMP1 | |
| SCHEMBL31126008 | 0.66 | CALCRL (0.48) | ADM2CALCBCALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073251-A1 | CONSTRAINED SPIROCYCLIC COMPOUNDS AS CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-06-19 | — | — | WO | disclosed |