Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598844 | 0.89 | PTGS2 (0.54) | PTGS1PGRPDE4APTGS2MEN1 | |
| Flurbiprofen SCHEMBL7581730 | 0.86 | AKR1C3 (0.52) | PTGS1PGRPDE4APTGS2MEN1 | |
| SCHEMBL135465 | 0.84 | PTGS1 (0.56) | PTGS1PGRPDE4APTGS2MEN1 | |
| SCHEMBL2722631 | 0.84 | PTGS1 (0.56) | PTGS1PGRPDE4APTGS2MEN1 | |
| SCHEMBL29380153 | 0.84 | PTGS1 (0.56) | PTGS1PGRPDE4APTGS2MEN1 | |
| SCHEMBL5605512 | 0.82 | PTGS1 (0.56) | PTGS1PGRPDE4APTGS2MEN1 | |
| SCHEMBL5140597 | 0.81 | PTGS2 (0.43) | PTGS1PTGS2LMNAMAPTTSHR | |
| SCHEMBL14190061 | 0.81 | PTGS2 (0.43) | PTGS1PTGS2LMNAMAPTTSHR | |
| SCHEMBL5494443 | 0.81 | PTGS2 (0.43) | PTGS1PTGS2LMNAMAPTTSHR | |
| SCHEMBL14188621 | 0.80 | PTGS2 (0.48) | PTGS1PDE4APTGS2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378412-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-05-27 | — | — | US | disclosed |