Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434959 | 0.85 | TSHR (0.36) | HPGDSMN1; SMN2P2RX7TSHRMEN1 | |
| SCHEMBL23400973 | 0.79 | TSHR (0.35) | HPGDSMN1; SMN2P2RX7TSHRMEN1 | |
| SCHEMBL4171724 | 0.79 | HPGD (0.46) | HPGDSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL23399191 | 0.79 | P2RX7 (0.30) | P2RX7TSHR | |
| SCHEMBL22412654 | 0.76 | P2RX7 (0.39) | HPGDSMN1; SMN2P2RX7TSHRMEN1 | |
| SCHEMBL18878191 | 0.76 | TSHR (0.32) | HPGDSMN1; SMN2P2RX7TSHRMEN1 | |
| SCHEMBL18884355 | 0.75 | HPGD (0.33) | HPGDSMN1; SMN2P2RX7TSHRMEN1 | |
| SCHEMBL21166086 | 0.73 | HPGD (0.35) | HPGDSMN1; SMN2P2RX7 | |
| SCHEMBL13148355 | 0.72 | HPGD (0.37) | HPGDSMN1; SMN2TSHR | |
| SCHEMBL15716050 | 0.70 | HPGD (0.36) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751897-B1 | Derivatives of Bodipy | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| WO-2008075172-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |