Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.56 |
| ▸ | PPARA | Q07869 | 9/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793221 | 0.82 | KMT2A (0.49) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL2666313 | 0.81 | PPARA (0.41) | PPARGPPARAMGLLMEN1CYP1A2 | |
| SCHEMBL16955057 | 0.78 | FFAR4 (0.42) | MGLLALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14190690 | 0.78 | PPARA (0.40) | PPARGPPARAMGLLMEN1CYP1A2 | |
| SCHEMBL5107914 | 0.77 | GRIN2D (0.55) | CYP1A2CYP2D6MAPTCYP2C19KMT2A | |
| SCHEMBL1796030 | 0.75 | KMT2A (0.51) | MEN1KMT2AALDH1A1GRIN2DGRIN3B | |
| SCHEMBL16957519 | 0.75 | CYP4F2 (0.61) | MEN1CYP3A4MAPTKMT2AALDH1A1 | |
| SCHEMBL16953625 | 0.73 | GRIN2D (0.44) | CYP1A2CYP2D6MAPTCYP2C19KMT2A | |
| SCHEMBL9996916 | 0.73 | PPARG (1.00) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL2666501 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1674097-B1 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2008-06-11 | — | — | EP | disclosed |