Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.84 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060687 | 0.92 | PTGDR2 (1.00) | PTGDR2PTGDRKDM4E | |
| SCHEMBL5055257 | 0.89 | PTGDR2 (0.96) | PTGDR2PTGDRKDM4E | |
| SCHEMBL5062519 | 0.85 | PTGDR2 (0.88) | PTGDR2PTGDRKDM4E | |
| SCHEMBL5056681 | 0.84 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL5514564 | 0.80 | PTGDR2 (0.72) | PTGDR2PTGDRKDM4EPOLB | |
| SCHEMBL5054962 | 0.79 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL5060247 | 0.78 | PTGDR2 (1.00) | PTGDR2PTGDRKDM4E | |
| SCHEMBL4497493 | 0.76 | PTGDR2 (1.00) | PTGDR2KDM4EPOLB | |
| SCHEMBL5056677 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL5062386 | 0.76 | PTGDR2 (1.00) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | 7TM PHARMA A/S (DK) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | HRH1, HRH2, HRH3 | PTGDR2 191/4885PTGDR 213/4885KDM4E 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.