Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056681 | 0.84 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL5544242 | 0.80 | PTGDR2 (0.76) | PTGDR2KDM4EPOLBCYP1A2GAA | |
| SCHEMBL14190870 | 0.80 | PTGDR2 (0.84) | PTGDR2KDM4EPOLBPTGDR | |
| SCHEMBL18456842 | 0.79 | PTGDR2 (0.46) | PTGDR2KDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL4497493 | 0.78 | PTGDR2 (1.00) | PTGDR2KDM4EPOLBCYP1A2MAPT | |
| SCHEMBL11872214 | 0.77 | CYP1A2 (1.00) | PTGDR2KDM4EPOLBCYP1A2GAA | |
| SCHEMBL9478688 | 0.77 | PTGDR2 (0.64) | PTGDR2KDM4EPOLBCYP1A2GAA | |
| SCHEMBL5514684 | 0.77 | KDM4E (0.49) | PTGDR2KDM4EPOLBCYP1A2GAA | |
| SCHEMBL5056677 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL5054962 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |