Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21202705 | 0.92 | ALDH1A1 (0.60) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL22200965 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL31392960 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL12440176 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL13317132 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL22121 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL17925477 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL12065399 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL20727180 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL22854462 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TP53TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848754-B1 | LOW SHRINKAGE AMINE-CURING EPOXY RESIN COMPOSITIONS COMPRISING A LACTONE | HENKEL KGAA (DE) | 2008-06-04 | — | — | EP | disclosed |