Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 10/20 | 0.38 |
| ▸ | THRA | P10827 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192445 | 0.97 | CYP2C9 (0.55) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192430 | 0.97 | CYP2C9 (0.55) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192521 | 0.94 | CYP2C9 (0.52) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192414 | 0.90 | CYP2C9 (0.63) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192550 | 0.90 | CYP2C9 (0.63) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192513 | 0.90 | CYP2C9 (0.43) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192524 | 0.89 | THRB (0.48) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192536 | 0.88 | CYP2C9 (0.42) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10898816 | 0.88 | CYP2C9 (0.66) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10938649 | 0.88 | CYP2C9 (0.66) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |