SCHEMBL14192533

SCHEMBL14192533

C=CC(=O)Cc1ccc(OC(=O)c2ccc(C3CCC(C4CCC(CCC)CC4)CC3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.48
MAPT P10636 5/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
THRB P10828 7/20 0.36
CACNA1G O43497 1/20 0.35
CACNA1H O95180 1/20 0.35
CACNA1I Q9P0X4 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
KLK1 P06870 2/20 0.34
PRSS1 P07477 2/20 0.34
TMPRSS2 O15393 1/20 0.34
TP53 P04637 1/20 0.34
THRA P10827 2/20 0.32
DGAT1 O75907 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14192521 0.90 CYP2C9 (0.52) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL14192397 0.89 CYP2C9 (0.53) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10910656 0.88 CYP2C9 (0.56) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10910653 0.88 CYP2C9 (0.56) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL14192445 0.87 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL14192430 0.87 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10910666 0.86 CYP2C9 (0.54) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10910678 0.86 CYP2C9 (0.54) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10910674 0.86 CYP2C9 (0.54) CYP2C9MAPTALDH1A1LMNAKMT2A
SCHEMBL10907936 0.86 CYP2C9 (0.54) CYP2C9MAPTALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7357964-B2 Liquid-crystalline vinyl ketone derivatives and their polymers CHISSO CORPORATION (JP) 2008-04-15 US disclosed