Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 7/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.32 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | CASP1 | P29466 | 5/20 | 0.31 |
| ▸ | CASP7 | P55210 | 5/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193138 | 0.92 | NPC1 (0.36) | NPC1USP2CYP1A2MEN1CYP3A4 | |
| SCHEMBL13870888 | 0.91 | NPC1 (0.35) | NPC1USP2CYP1A2MEN1CYP3A4 | |
| SCHEMBL13865958 | 0.89 | NPC1 (0.33) | NPC1USP2CYP1A2MEN1CYP3A4 | |
| SCHEMBL13870977 | 0.83 | EP300 (0.32) | NPC1 | |
| SCHEMBL13865960 | 0.83 | NPC1 (0.34) | NPC1USP2CYP1A2MEN1CYP3A4 | |
| SCHEMBL13865961 | 0.83 | NPC1 (0.36) | NPC1USP2CYP1A2MEN1CYP3A4 | |
| SCHEMBL13865957 | 0.81 | NPC1 (0.35) | NPC1USP2CYP1A2MEN1CYP3A4 | |
| SCHEMBL13865870 | 0.78 | NPC1 (0.38) | NPC1 | |
| SCHEMBL13865967 | 0.78 | — | — | |
| SCHEMBL13865913 | 0.77 | NPC1 (0.39) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388010-B2 | Quinoxalinone derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-17 | — | — | US | disclosed |