Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865979 | 0.91 | EP300 (0.30) | EP300CREBBP | |
| SCHEMBL14193139 | 0.85 | EP300 (0.36) | EP300CREBBPNPC1 | |
| SCHEMBL14193138 | 0.84 | NPC1 (0.36) | NPC1 | |
| SCHEMBL14193774 | 0.83 | NPC1 (0.35) | NPC1 | |
| SCHEMBL13865960 | 0.78 | NPC1 (0.34) | NPC1 | |
| SCHEMBL13865967 | 0.77 | — | — | |
| SCHEMBL13865982 | 0.76 | EP300 (0.34) | EP300CREBBPNPC1 | |
| SCHEMBL13865972 | 0.75 | NPC1 (0.31) | NPC1 | |
| SCHEMBL13865958 | 0.75 | NPC1 (0.33) | NPC1 | |
| SCHEMBL13865985 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137597-A1 | Novel quinoxalinone derivatives | MSD K.K. (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137597-A1 | Novel quinoxalinone derivatives | NDUFB1, NDUFB6, NDUFB7 | EP300 2892/4885CREBBP 1662/4885NPC1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.