Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498087 | 0.94 | MEN1 (0.74) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL28754776 | 0.83 | KMT2A (0.73) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL9479370 | 0.81 | KMT2A (1.00) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL92717 | 0.81 | KMT2A (1.00) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL1952693 | 0.81 | KMT2A (1.00) | KMT2AMEN1GAACA1CA2 | |
| Ammonia Solution, Strong SCHEMBL15741206 | 0.80 | KMT2A (0.97) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL2240008 | 0.78 | CA1 (0.71) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL1417537 | 0.78 | CA1 (0.71) | KMT2AMEN1GAACA1CA2 | |
| Phenol SCHEMBL28153349 | 0.76 | KMT2A (0.67) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL19119164 | 0.75 | CA12 (1.00) | KMT2AMEN1GAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297241-A1 | SUBSTITUTED TRIAZINE COMPOSITIONS AND METHODS FOR PRODUCING SAME | Chemtura Corporation (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010005631-A1 | SUBSTITUTED TRIAZINE COMPOSITIONS AND METHODS FOR PRODUCING SAME | CHEMTURA CORPORATION (US) | 2010-01-14 | — | — | WO | disclosed |